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BMS-536924

Synonyms

SourcesNames Used
GDSC1000, CTRPv2BMS-536924
PharmacoGx BMS-536924

External IDs

DatabaseIdentifier
Smiles: CC1=CC(=CC2=C1NC(=C3C(=CC=NC3=O)NCC(C4=CC(=CC=C4)Cl)O)N2)N5CCOCC5
Inchikey: UGQMURPIMYALPH-PZJQAWQVSA-N
Pubchem: 10390396

Annotated Targets

AKT1, CCNE1, CDK2, CYP3A4, ERBB2, IGF1R, KDR, LCK, MAPK1, MET, PDGFRA, PDGFRB, INSR

FDA Approval Status

Not Approved
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Top molecular features associated with response to BMS-536924


Feature TypeStandardized
Nominal ANOVA
mRNA KCNE5 GDSC1000 pan-cancer AAC 0.17 6e-08
mRNA IL6R GDSC1000 pan-cancer AAC 0.18 6e-08
mRNA P2RX1 GDSC1000 pan-cancer AAC 0.21 7e-08
mRNA GOLGA8S CTRPv2 pan-cancer AAC 0.19 1e-07
mRNA ITM2C CTRPv2 pan-cancer AAC 0.19 1e-07
mRNA CHSY1 CTRPv2 pan-cancer AAC 0.21 1e-07
mRNA FGFR3 CTRPv2 pan-cancer AAC 0.18 1e-07
mRNA RP3-369A17.6 CTRPv2 pan-cancer AAC -0.21 1e-07
mRNA CHST12 CTRPv2 pan-cancer AAC 0.19 1e-07
mRNA SWAP70 CTRPv2 pan-cancer AAC -0.19 2e-07
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