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BI-2536

Synonyms

SourcesNames Used
GDSC1000, CTRPv2BI-2536
FIMMBI 2536
PharmacoGx BI-2536

External IDs

DatabaseIdentifier
Smiles: CCC1C(=O)N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C(C=C4)C(=O)NC5CCN(CC5)C)OC)C
Inchikey: XQVVPGYIWAGRNI-JOCHJYFZSA-N
Pubchem: 11364421

Annotated Targets

BRD4, PLK1, PLK2, PLK3

FDA Approval Status

Not Approved
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Top molecular features associated with response to BI-2536


Feature TypeStandardized
Nominal ANOVA
mRNA TAF5 CTRPv2 pan-cancer AAC 0.3 2e-18
mRNA CD63 CTRPv2 pan-cancer AAC -0.31 4e-16
mRNA SAFB CTRPv2 pan-cancer AAC 0.28 2e-15
mRNA PRPF38A CTRPv2 pan-cancer AAC 0.27 3e-15
mRNA ANP32A CTRPv2 pan-cancer AAC 0.27 3e-15
mRNA HNRNPU CTRPv2 pan-cancer AAC 0.26 4e-15
mRNA ORC1 CTRPv2 pan-cancer AAC 0.28 4e-15
mRNA TUBGCP4 CTRPv2 pan-cancer AAC 0.25 1e-14
mRNA MCM2 CTRPv2 pan-cancer AAC 0.27 2e-14
mRNA NUP133 CTRPv2 pan-cancer AAC 0.24 5e-14
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