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WH-4-023

WH-4-023

Synonyms

Sources	Names Used
GDSC1000	WH-4-023
PharmacoGx	WH-4-023

External IDs

Database	Identifier
Smiles:	CC1=C(C(=CC=C1)C)OC(=O)N(C2=C(C=C(C=C2)OC)OC)C3=NC(=NC=C3)NC4=CC=C(C=C4)N5CCN(CC5)C
Inchikey:	NBTNHSGBRGTFJS-UHFFFAOYSA-N
Pubchem:	11844351

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to WH-4-023

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PUM2	GDSC1000	pan-cancer	AAC	-0.21	0.0003
mRNA	USP50	GDSC1000	pan-cancer	AAC	0.18	0.0003
mRNA	PLD6	GDSC1000	pan-cancer	AAC	-0.19	0.0003
mRNA	HSPE1	GDSC1000	pan-cancer	AAC	-0.2	0.0003
mRNA	LPAR5	GDSC1000	pan-cancer	AAC	0.2	0.0003
mRNA	TUBB1	GDSC1000	pan-cancer	AAC	0.17	0.0003
mRNA	DTD1	GDSC1000	pan-cancer	AAC	-0.18	0.0003
mRNA	CCND3	GDSC1000	pan-cancer	AAC	0.21	0.0003
mRNA	TRAF3IP3	GDSC1000	pan-cancer	AAC	-0.26	0.0003
mRNA	SNAP23	GDSC1000	pan-cancer	AAC	0.23	0.0003

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