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GNF-2

GNF-2

Synonyms

Sources	Names Used
GDSC1000	GNF-2
PharmacoGx	GNF-2

External IDs

Database	Identifier
Smiles:	C1=CC(=CC(=C1)C(=O)N)C2=CC(=NC=N2)NC3=CC=C(C=C3)OC(F)(F)F
Inchikey:	WEVYNIUIFUYDGI-UHFFFAOYSA-N
Pubchem:	5311510

Annotated Targets

ABL1, BCR

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to GNF-2

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ACTR8	GDSC1000	pan-cancer	AAC	-0.12	0.04
mRNA	ACTRT1	GDSC1000	pan-cancer	AAC	0.12	0.02
mRNA	ADAM10	GDSC1000	pan-cancer	AAC	0.14	0.02
mRNA	ADAM9	GDSC1000	pan-cancer	AAC	0.15	0.04
mRNA	ADAMTS14	GDSC1000	pan-cancer	AAC	0.11	0.03
mRNA	ADAMTS9	GDSC1000	pan-cancer	AAC	0.16	0.006
mRNA	ADAMTSL4	GDSC1000	pan-cancer	AAC	0.16	0.003
mRNA	ADAMTSL5	GDSC1000	pan-cancer	AAC	0.1	0.06
mRNA	ADARB2	GDSC1000	pan-cancer	AAC	-0.12	0.02
mRNA	ADCK5	GDSC1000	pan-cancer	AAC	0.1	0.06

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