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GNF-2

GNF-2

Synonyms

Sources	Names Used
GDSC1000	GNF-2
PharmacoGx	GNF-2

External IDs

Database	Identifier
Smiles:	C1=CC(=CC(=C1)C(=O)N)C2=CC(=NC=N2)NC3=CC=C(C=C3)OC(F)(F)F
Inchikey:	WEVYNIUIFUYDGI-UHFFFAOYSA-N
Pubchem:	5311510

Annotated Targets

ABL1, BCR

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to GNF-2

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	HSPG2	GDSC1000	pan-cancer	AAC	0.28	7e-06
mRNA	MED15	GDSC1000	pan-cancer	AAC	0.29	6e-07
mRNA	CISH	GDSC1000	pan-cancer	AAC	0.29	7e-08
mRNA	LIN28A	GDSC1000	pan-cancer	AAC	0.3	0.002
mRNA	PPIC	GDSC1000	pan-cancer	AAC	0.3	5e-05
mRNA	SERPINH1	GDSC1000	pan-cancer	AAC	0.3	8e-06
mRNA	TJP1	GDSC1000	pan-cancer	AAC	0.31	0.003
mRNA	IFITM3	GDSC1000	pan-cancer	AAC	0.31	6e-06
mRNA	GAB2	GDSC1000	pan-cancer	AAC	0.32	6e-10
mRNA	FAM129B	GDSC1000	pan-cancer	AAC	0.36	6e-06

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