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GNF-2

GNF-2

Synonyms

Sources	Names Used
GDSC1000	GNF-2
PharmacoGx	GNF-2

External IDs

Database	Identifier
Smiles:	C1=CC(=CC(=C1)C(=O)N)C2=CC(=NC=N2)NC3=CC=C(C=C3)OC(F)(F)F
Inchikey:	WEVYNIUIFUYDGI-UHFFFAOYSA-N
Pubchem:	5311510

Annotated Targets

ABL1, BCR

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to GNF-2

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	UROC1	GDSC1000	pan-cancer	AAC	0.17	0.001
mRNA	CACNA1A	GDSC1000	pan-cancer	AAC	-0.19	0.001
mRNA	ANO5	GDSC1000	pan-cancer	AAC	0.17	0.001
mRNA	SYNE1	GDSC1000	pan-cancer	AAC	-0.18	0.001
mRNA	CRYBA1	GDSC1000	pan-cancer	AAC	0.17	0.001
mRNA	ZNF648	GDSC1000	pan-cancer	AAC	0.16	0.001
mRNA	CPT2	GDSC1000	pan-cancer	AAC	-0.17	0.001
mRNA	MTERF1	GDSC1000	pan-cancer	AAC	-0.17	0.001
mRNA	TONSL	GDSC1000	pan-cancer	AAC	0.17	0.001
mRNA	CD151	GDSC1000	pan-cancer	AAC	0.22	0.001

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