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AZ628

Synonyms

SourcesNames Used
GDSC1000AZ628
PharmacoGx AZ628

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(C)(C)C#N)NC3=CC4=C(C=C3)N=CN(C4=O)C
Inchikey: ZGBGPEDJXCYQPH-UHFFFAOYSA-N
Pubchem: 11676786

Annotated Targets

BRAF, RAF1

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZ628


Feature TypeStandardized
Nominal ANOVA
mRNA RABGAP1 GDSC1000 pan-cancer AAC -0.24 1e-05
mRNA RNASE2 GDSC1000 pan-cancer AAC 0.21 1e-05
mRNA IFITM3 GDSC1000 pan-cancer AAC 0.28 1e-05
mRNA PPP4R3A GDSC1000 pan-cancer AAC -0.24 1e-05
mRNA RFTN1 GDSC1000 pan-cancer AAC -0.26 1e-05
mRNA BIRC3 GDSC1000 pan-cancer AAC -0.23 1e-05
mRNA RNH1 GDSC1000 pan-cancer AAC 0.22 1e-05
mRNA AFDN GDSC1000 pan-cancer AAC -0.23 1e-05
mRNA CSPG4 GDSC1000 pan-cancer AAC 0.26 1e-05
mRNA AIF1 GDSC1000 pan-cancer AAC 0.24 1e-05
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