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AZ628

Synonyms

SourcesNames Used
GDSC1000AZ628
PharmacoGx AZ628

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(C)(C)C#N)NC3=CC4=C(C=C3)N=CN(C4=O)C
Inchikey: ZGBGPEDJXCYQPH-UHFFFAOYSA-N
Pubchem: 11676786

Annotated Targets

BRAF, RAF1

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZ628


Feature TypeStandardized
Nominal ANOVA
mRNA ANGPT1 GDSC1000 pan-cancer AAC 0.28 2e-08
mRNA TOR1AIP1 GDSC1000 pan-cancer AAC 0.27 3e-08
mRNA GBE1 GDSC1000 pan-cancer AAC 0.33 3e-08
mRNA CTBP2 GDSC1000 pan-cancer AAC 0.34 3e-08
mRNA ADGRA2 GDSC1000 pan-cancer AAC 0.3 4e-08
mRNA SYNE2 GDSC1000 pan-cancer AAC -0.27 4e-08
mRNA PYCARD GDSC1000 pan-cancer AAC 0.31 4e-08
mRNA SERPINH1 GDSC1000 pan-cancer AAC 0.34 7e-08
mRNA TMEM55A GDSC1000 pan-cancer AAC 0.28 8e-08
mRNA FKBP10 GDSC1000 pan-cancer AAC 0.35 8e-08
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