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AZ628

Synonyms

SourcesNames Used
GDSC1000AZ628
PharmacoGx AZ628

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(C)(C)C#N)NC3=CC4=C(C=C3)N=CN(C4=O)C
Inchikey: ZGBGPEDJXCYQPH-UHFFFAOYSA-N
Pubchem: 11676786

Annotated Targets

BRAF, RAF1

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZ628


Feature TypeStandardized
Nominal ANOVA
mRNA FAR2 GDSC1000 pan-cancer AAC 0.25 1e-07
mRNA ENG GDSC1000 pan-cancer AAC 0.26 2e-07
mRNA SGCD GDSC1000 pan-cancer AAC 0.3 2e-07
mRNA EMILIN2 GDSC1000 pan-cancer AAC 0.25 2e-07
mRNA ZFP36L2 GDSC1000 pan-cancer AAC 0.28 2e-07
mRNA WFDC1 GDSC1000 pan-cancer AAC 0.24 2e-07
mRNA TOP1MT GDSC1000 pan-cancer AAC 0.26 2e-07
mRNA ARRB1 GDSC1000 pan-cancer AAC 0.25 2e-07
mRNA SCGB3A1 GDSC1000 pan-cancer AAC 0.24 2e-07
mRNA TIMP1 GDSC1000 pan-cancer AAC 0.27 3e-07
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