1. Home/
  2. Compounds/
  3. AZ628

AZ628

Synonyms

SourcesNames Used
GDSC1000AZ628
PharmacoGx AZ628

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(C)(C)C#N)NC3=CC4=C(C=C3)N=CN(C4=O)C
Inchikey: ZGBGPEDJXCYQPH-UHFFFAOYSA-N
Pubchem: 11676786

Annotated Targets

BRAF, RAF1

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to AZ628


Feature TypeStandardized
Nominal ANOVA
mRNA IRAK3 GDSC1000 pan-cancer AAC 0.22 7e-06
mRNA P3H4 GDSC1000 pan-cancer AAC 0.3 7e-06
mRNA SRPX GDSC1000 pan-cancer AAC 0.3 7e-06
mRNA SIRPA GDSC1000 pan-cancer AAC 0.25 7e-06
mRNA ZEB2 GDSC1000 pan-cancer AAC 0.24 7e-06
mRNA EML5 GDSC1000 pan-cancer AAC -0.29 7e-06
mRNA FRAT1 GDSC1000 pan-cancer AAC 0.24 7e-06
mRNA KCNE5 GDSC1000 pan-cancer AAC 0.21 8e-06
mRNA CD63 GDSC1000 pan-cancer AAC 0.27 8e-06
mRNA UBL3 GDSC1000 pan-cancer AAC 0.24 8e-06
Download CSV