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AZ628

Synonyms

SourcesNames Used
GDSC1000AZ628
PharmacoGx AZ628

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(C)(C)C#N)NC3=CC4=C(C=C3)N=CN(C4=O)C
Inchikey: ZGBGPEDJXCYQPH-UHFFFAOYSA-N
Pubchem: 11676786

Annotated Targets

BRAF, RAF1

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZ628


Feature TypeStandardized
Nominal ANOVA
mRNA IKBIP GDSC1000 pan-cancer AAC 0.27 4e-06
mRNA LRRC3 GDSC1000 pan-cancer AAC 0.23 4e-06
mRNA C9orf72 GDSC1000 pan-cancer AAC -0.24 4e-06
mRNA ATP8A1 GDSC1000 pan-cancer AAC -0.24 4e-06
mRNA APOC1 GDSC1000 pan-cancer AAC 0.22 4e-06
mRNA GAS7 GDSC1000 pan-cancer AAC 0.26 4e-06
mRNA KIR3DL1 GDSC1000 pan-cancer AAC 0.22 4e-06
mRNA SLC38A10 GDSC1000 pan-cancer AAC 0.22 5e-06
mRNA FHL3 GDSC1000 pan-cancer AAC 0.22 5e-06
mRNA GPX8 GDSC1000 pan-cancer AAC 0.35 5e-06
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