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AZ628

Synonyms

SourcesNames Used
GDSC1000AZ628
PharmacoGx AZ628

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(C)(C)C#N)NC3=CC4=C(C=C3)N=CN(C4=O)C
Inchikey: ZGBGPEDJXCYQPH-UHFFFAOYSA-N
Pubchem: 11676786

Annotated Targets

BRAF, RAF1

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZ628


Feature TypeStandardized
Nominal ANOVA
mRNA AKIRIN2 GDSC1000 pan-cancer AAC -0.18 0.0003
mRNA DHRS1 GDSC1000 pan-cancer AAC -0.18 0.0003
mRNA S100A1 GDSC1000 pan-cancer AAC 0.2 0.0003
mRNA KIAA0355 GDSC1000 pan-cancer AAC -0.18 0.0003
mRNA HTRA1 GDSC1000 pan-cancer AAC 0.26 0.0003
mRNA CARD6 GDSC1000 pan-cancer AAC 0.18 0.0003
mRNA LGALS3BP GDSC1000 pan-cancer AAC 0.23 0.0003
mRNA MURC GDSC1000 pan-cancer AAC -0.2 0.0003
mRNA FAM210A GDSC1000 pan-cancer AAC 0.2 0.0003
mRNA FAM135A GDSC1000 pan-cancer AAC -0.18 0.0003
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