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AZ628

Synonyms

SourcesNames Used
GDSC1000AZ628
PharmacoGx AZ628

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(C)(C)C#N)NC3=CC4=C(C=C3)N=CN(C4=O)C
Inchikey: ZGBGPEDJXCYQPH-UHFFFAOYSA-N
Pubchem: 11676786

Annotated Targets

BRAF, RAF1

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZ628


Feature TypeStandardized
Nominal ANOVA
mRNA C14orf166 GDSC1000 pan-cancer AAC -0.14 0.008
mRNA NAALADL2 GDSC1000 pan-cancer AAC -0.16 0.008
mRNA EPSTI1 GDSC1000 pan-cancer AAC -0.14 0.008
mRNA C21orf91 GDSC1000 pan-cancer AAC -0.14 0.008
mRNA ZNF738 GDSC1000 pan-cancer AAC -0.13 0.008
mRNA C12orf49 GDSC1000 pan-cancer AAC -0.13 0.008
mRNA RING1 GDSC1000 pan-cancer AAC -0.13 0.008
mRNA ITGB1BP2 GDSC1000 pan-cancer AAC -0.13 0.008
mRNA TRPV4 GDSC1000 pan-cancer AAC 0.15 0.008
mRNA BTG3 GDSC1000 pan-cancer AAC -0.13 0.008
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