1. Home/
  2. Compounds/
  3. AZ628

AZ628

Synonyms

SourcesNames Used
GDSC1000AZ628
PharmacoGx AZ628

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(C)(C)C#N)NC3=CC4=C(C=C3)N=CN(C4=O)C
Inchikey: ZGBGPEDJXCYQPH-UHFFFAOYSA-N
Pubchem: 11676786

Annotated Targets

BRAF, RAF1

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to AZ628


Feature TypeStandardized
Nominal ANOVA
mRNA TNFRSF1A GDSC1000 pan-cancer AAC 0.31 3e-09
mRNA ACTN1 GDSC1000 pan-cancer AAC 0.36 3e-09
mRNA GCH1 GDSC1000 pan-cancer AAC -0.3 4e-09
mRNA PELI1 GDSC1000 pan-cancer AAC -0.29 4e-09
mRNA DAAM1 GDSC1000 pan-cancer AAC -0.3 6e-09
mRNA MFSD12 GDSC1000 pan-cancer AAC 0.33 6e-09
mRNA ETV4 GDSC1000 pan-cancer AAC 0.31 7e-09
mRNA CD68 GDSC1000 pan-cancer AAC 0.31 9e-09
mRNA PYGL GDSC1000 pan-cancer AAC 0.29 1e-08
mRNA MMP14 GDSC1000 pan-cancer AAC 0.36 1e-08
Download CSV