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Tipifarnib

Synonyms

SourcesNames Used
GDSC1000, FIMMTipifarnib
PharmacoGx Tipifarnib

External IDs

DatabaseIdentifier
Smiles: CN1C=NC=C1C(C2=CC=C(C=C2)Cl)(C3=CC4=C(C=C3)N(C(=O)C=C4C5=CC(=CC=C5)Cl)C)N
Inchikey: PLHJCIYEEKOWNM-HHHXNRCGSA-N
Pubchem: 159324

FDA Approval Status

Not Approved
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Top molecular features associated with response to Tipifarnib


Feature TypeStandardized
Nominal ANOVA
mRNA IQCB1 GDSC1000 pan-cancer AAC 0.093 0.02
mRNA GDAP1 FIMM pan-cancer AAC 0.29 0.02
mRNA EML5 GDSC1000 pan-cancer AAC -0.1 0.02
mRNA BTBD17 GDSC1000 pan-cancer AAC -0.082 0.02
mRNA DEC1 GDSC1000 pan-cancer AAC 0.078 0.02
mRNA PRDX6 GDSC1000 pan-cancer AAC 0.081 0.02
mRNA ADAMTS8 FIMM pan-cancer AAC 0.28 0.02
mRNA MKNK1 FIMM pan-cancer AAC -0.41 0.02
mRNA MAP3K5 FIMM pan-cancer AAC -0.28 0.02
mRNA ASH2L GDSC1000 pan-cancer AAC -0.083 0.02
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