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GSK-1904529A

Synonyms

SourcesNames Used
GDSC1000GSK1904529A
PharmacoGx GSK-1904529A

External IDs

DatabaseIdentifier
Smiles: CCC1=CC(=C(C=C1N2CCC(CC2)N3CCN(CC3)S(=O)(=O)C)OC)NC4=NC=CC(=N4)C5=C(N=C6N5C=CC=C6)C7=CC(=C(C=C7)OC)C(=O)NC8=C(C=CC=C8F)F
Inchikey: MOSKATHMXWSZTQ-UHFFFAOYSA-N
Pubchem: 25124816

Annotated Targets

IGF1R, INSR

FDA Approval Status

Not Approved
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Top molecular features associated with response to GSK-1904529A


Feature TypeStandardized
Nominal ANOVA
mRNA ZFAND3 GDSC1000 pan-cancer AAC 0.13 0.0003
mRNA C5orf30 GDSC1000 pan-cancer AAC -0.12 0.0003
mRNA RNASEH2A GDSC1000 pan-cancer AAC -0.12 0.0003
mRNA SLC30A3 GDSC1000 pan-cancer AAC -0.13 0.0003
mRNA TTC12 GDSC1000 pan-cancer AAC 0.13 0.0003
mRNA AP4B1 GDSC1000 pan-cancer AAC -0.14 0.0003
mRNA VRK1 GDSC1000 pan-cancer AAC -0.14 0.0003
mRNA NR4A3 GDSC1000 pan-cancer AAC 0.13 0.0003
mRNA MID2 GDSC1000 pan-cancer AAC 0.13 0.0003
mRNA ADSSL1 GDSC1000 pan-cancer AAC 0.13 0.0004
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