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Pazopanib

Pazopanib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Pazopanib
PharmacoGx	Pazopanib

External IDs

Database	Identifier
Smiles:	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Inchikey:	MQHIQUBXFFAOMK-UHFFFAOYSA-N
Pubchem:	11525740

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Pazopanib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TRH	FIMM	pan-cancer	AAC	0.72	4e-06
mRNA	KHDRBS3	GDSC1000	pan-cancer	AAC	-0.17	5e-06
mRNA	SLC27A1	GDSC1000	pan-cancer	AAC	0.16	5e-06
mRNA	RUNX1T1	FIMM	pan-cancer	AAC	0.71	5e-06
mRNA	MAPT	GDSC1000	pan-cancer	AAC	-0.17	6e-06
mRNA	LILRB2	GDSC1000	pan-cancer	AAC	0.16	6e-06
mRNA	ERG	FIMM	pan-cancer	AAC	0.76	6e-06
mRNA	DOCK1	GDSC1000	pan-cancer	AAC	0.18	6e-06
mRNA	MXRA8	GDSC1000	pan-cancer	AAC	0.16	7e-06
mRNA	EPB41	GDSC1000	pan-cancer	AAC	-0.17	8e-06

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