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Pazopanib

Pazopanib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Pazopanib
PharmacoGx	Pazopanib

External IDs

Database	Identifier
Smiles:	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Inchikey:	MQHIQUBXFFAOMK-UHFFFAOYSA-N
Pubchem:	11525740

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Pazopanib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	B3GNTL1	FIMM	pan-cancer	AAC	0.65	0.01
mRNA	DNASE2B	FIMM	pan-cancer	AAC	0.65	0.0002
mRNA	RRP8	FIMM	pan-cancer	AAC	0.65	0.004
mRNA	LRRC3	FIMM	pan-cancer	AAC	0.64	0.0007
mRNA	A1CF	FIMM	pan-cancer	AAC	0.64	0.002
mRNA	USP15	FIMM	pan-cancer	AAC	0.63	0.003
mRNA	P2RY13	FIMM	pan-cancer	AAC	0.63	0.0002
mRNA	SLC18A2	FIMM	pan-cancer	AAC	0.63	0.0002
mRNA	ATP2A3	FIMM	pan-cancer	AAC	0.63	0.02
mRNA	EGFL7	FIMM	pan-cancer	AAC	0.62	0.0002

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