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Pazopanib

Pazopanib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Pazopanib
PharmacoGx	Pazopanib

External IDs

Database	Identifier
Smiles:	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Inchikey:	MQHIQUBXFFAOMK-UHFFFAOYSA-N
Pubchem:	11525740

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Pazopanib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MYL12A	FIMM	pan-cancer	AAC	-0.56	0.001
mRNA	SEL1L3	FIMM	pan-cancer	AAC	-0.57	0.001
mRNA	NRXN2	FIMM	pan-cancer	AAC	0.58	0.001
mRNA	SRP72	FIMM	pan-cancer	AAC	0.61	0.001
mRNA	ANP32E	FIMM	pan-cancer	AAC	-0.67	0.001
mRNA	HLA-C	FIMM	pan-cancer	AAC	-0.58	0.001
mRNA	UROD	FIMM	pan-cancer	AAC	0.54	0.001
mRNA	TFDP3	FIMM	pan-cancer	AAC	0.58	0.002
mRNA	XPA	FIMM	pan-cancer	AAC	0.56	0.002
mRNA	FASTKD3	FIMM	pan-cancer	AAC	0.58	0.002

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