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Pazopanib

Pazopanib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Pazopanib
PharmacoGx	Pazopanib

External IDs

Database	Identifier
Smiles:	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Inchikey:	MQHIQUBXFFAOMK-UHFFFAOYSA-N
Pubchem:	11525740

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Pazopanib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	DNAJC13	FIMM	pan-cancer	AAC	0.39	0.03
mRNA	KCNK3	GDSC1000	pan-cancer	AAC	-0.085	0.03
mRNA	ETV6	FIMM	pan-cancer	AAC	0.59	0.03
mRNA	FUT11	GDSC1000	pan-cancer	AAC	0.08	0.03
mRNA	GNAS	GDSC1000	pan-cancer	AAC	-0.076	0.03
mRNA	CPA1	GDSC1000	pan-cancer	AAC	0.075	0.03
mRNA	ZNF433	GDSC1000	pan-cancer	AAC	0.081	0.03
mRNA	DPH5	FIMM	pan-cancer	AAC	0.38	0.03
mRNA	TNN	FIMM	pan-cancer	AAC	-0.45	0.03
mRNA	MAP4K5	FIMM	pan-cancer	AAC	0.43	0.03

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