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Pazopanib

Pazopanib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Pazopanib
PharmacoGx	Pazopanib

External IDs

Database	Identifier
Smiles:	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Inchikey:	MQHIQUBXFFAOMK-UHFFFAOYSA-N
Pubchem:	11525740

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Pazopanib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	BMPR1B	FIMM	pan-cancer	AAC	0.39	0.02
mRNA	PLA2G2A	FIMM	pan-cancer	AAC	0.39	0.02
mRNA	MCM7	GDSC1000	pan-cancer	AAC	-0.08	0.02
mRNA	MESP2	GDSC1000	pan-cancer	AAC	0.078	0.02
mRNA	ZFP64	GDSC1000	pan-cancer	AAC	0.082	0.02
mRNA	HHLA2	GDSC1000	pan-cancer	AAC	0.076	0.02
mRNA	TIMM9	FIMM	pan-cancer	AAC	0.4	0.02
mRNA	C14orf166	FIMM	pan-cancer	AAC	0.41	0.02
mRNA	HHIPL2	GDSC1000	pan-cancer	AAC	0.078	0.02
mRNA	MAGED2	FIMM	pan-cancer	AAC	0.43	0.02

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