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Pazopanib

Pazopanib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Pazopanib
PharmacoGx	Pazopanib

External IDs

Database	Identifier
Smiles:	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Inchikey:	MQHIQUBXFFAOMK-UHFFFAOYSA-N
Pubchem:	11525740

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Pazopanib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	COL26A1	GDSC1000	pan-cancer	AAC	0.08	0.03
mRNA	PIEZO1	GDSC1000	pan-cancer	AAC	0.08	0.03
mRNA	TRIOBP	GDSC1000	pan-cancer	AAC	0.085	0.03
mRNA	RPS19	FIMM	pan-cancer	AAC	0.4	0.03
mRNA	SOX12	FIMM	pan-cancer	AAC	0.4	0.03
mRNA	PBX3	FIMM	pan-cancer	AAC	-0.43	0.03
mRNA	PIGX	GDSC1000	pan-cancer	AAC	-0.076	0.03
mRNA	MAPK13	GDSC1000	pan-cancer	AAC	-0.092	0.03
mRNA	TRPS1	GDSC1000	pan-cancer	AAC	0.086	0.03
mRNA	ADHFE1	GDSC1000	pan-cancer	AAC	0.074	0.03

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