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Pazopanib

Pazopanib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Pazopanib
PharmacoGx	Pazopanib

External IDs

Database	Identifier
Smiles:	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Inchikey:	MQHIQUBXFFAOMK-UHFFFAOYSA-N
Pubchem:	11525740

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Pazopanib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MAD1L1	GDSC1000	pan-cancer	AAC	0.14	0.0002
mRNA	EGFL7	FIMM	pan-cancer	AAC	0.62	0.0002
mRNA	DNASE2B	FIMM	pan-cancer	AAC	0.65	0.0002
mRNA	PTRF	GDSC1000	pan-cancer	AAC	0.16	0.0002
mRNA	GLIS1	GDSC1000	pan-cancer	AAC	0.14	0.0002
mRNA	PKIA	GDSC1000	pan-cancer	AAC	-0.14	0.0002
mRNA	CYR61	GDSC1000	pan-cancer	AAC	0.18	0.0002
mRNA	PLOD1	GDSC1000	pan-cancer	AAC	0.15	0.0002
mRNA	RNF216	GDSC1000	pan-cancer	AAC	0.13	0.0002
mRNA	STRBP	GDSC1000	pan-cancer	AAC	-0.15	0.0002

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