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Pazopanib

Pazopanib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Pazopanib
PharmacoGx	Pazopanib

External IDs

Database	Identifier
Smiles:	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Inchikey:	MQHIQUBXFFAOMK-UHFFFAOYSA-N
Pubchem:	11525740

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Pazopanib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	EPHA5	GDSC1000	pan-cancer	AAC	0.14	0.0001
mRNA	IRS2	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	TAS2R5	GDSC1000	pan-cancer	AAC	0.13	0.0001
mRNA	FAM184A	GDSC1000	pan-cancer	AAC	-0.15	0.0001
mRNA	ATP1A1	GDSC1000	pan-cancer	AAC	-0.15	0.0001
mRNA	SEC11C	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	AMER2	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	HSPG2	GDSC1000	pan-cancer	AAC	0.15	0.0001
mRNA	PARVA	GDSC1000	pan-cancer	AAC	0.18	0.0001
mRNA	PPM1F	GDSC1000	pan-cancer	AAC	0.13	0.0002

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