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Pazopanib

Pazopanib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Pazopanib
PharmacoGx	Pazopanib

External IDs

Database	Identifier
Smiles:	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Inchikey:	MQHIQUBXFFAOMK-UHFFFAOYSA-N
Pubchem:	11525740

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Pazopanib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CD200	FIMM	pan-cancer	AAC	0.5	0.006
mRNA	SLC38A2	GDSC1000	pan-cancer	AAC	0.099	0.006
mRNA	CXCR4	FIMM	pan-cancer	AAC	-0.64	0.006
mRNA	SEC31B	FIMM	pan-cancer	AAC	0.68	0.006
mRNA	HCN3	GDSC1000	pan-cancer	AAC	-0.1	0.006
mRNA	ABCE1	FIMM	pan-cancer	AAC	0.52	0.006
mRNA	PLPPR2	GDSC1000	pan-cancer	AAC	0.11	0.006
mRNA	FAM57B	GDSC1000	pan-cancer	AAC	-0.1	0.006
mRNA	TCIRG1	GDSC1000	pan-cancer	AAC	0.1	0.006
mRNA	LY86	FIMM	pan-cancer	AAC	-0.71	0.006

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