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Pazopanib

Pazopanib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Pazopanib
PharmacoGx	Pazopanib

External IDs

Database	Identifier
Smiles:	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Inchikey:	MQHIQUBXFFAOMK-UHFFFAOYSA-N
Pubchem:	11525740

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Pazopanib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	LSAMP	GDSC1000	pan-cancer	AAC	-0.11	0.003
mRNA	TRIM8	GDSC1000	pan-cancer	AAC	0.11	0.003
mRNA	VSTM1	GDSC1000	pan-cancer	AAC	0.097	0.003
mRNA	RGSL1	GDSC1000	pan-cancer	AAC	0.098	0.003
mRNA	LGSN	FIMM	pan-cancer	AAC	0.53	0.003
mRNA	EML6	GDSC1000	pan-cancer	AAC	-0.11	0.003
mRNA	JAKMIP1	GDSC1000	pan-cancer	AAC	-0.11	0.003
mRNA	EZH2	GDSC1000	pan-cancer	AAC	-0.11	0.003
mRNA	B4GALT3	GDSC1000	pan-cancer	AAC	-0.1	0.003
mRNA	USP27X	FIMM	pan-cancer	AAC	0.53	0.003

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