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Pazopanib

Pazopanib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Pazopanib
PharmacoGx	Pazopanib

External IDs

Database	Identifier
Smiles:	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Inchikey:	MQHIQUBXFFAOMK-UHFFFAOYSA-N
Pubchem:	11525740

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Pazopanib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ITGAM	GDSC1000	pan-cancer	AAC	0.11	0.002
mRNA	NPC1	GDSC1000	pan-cancer	AAC	0.11	0.002
mRNA	P3H4	GDSC1000	pan-cancer	AAC	0.13	0.002
mRNA	THBS3	GDSC1000	pan-cancer	AAC	0.11	0.002
mRNA	KAT6B	FIMM	pan-cancer	AAC	0.57	0.002
mRNA	SMIM3	GDSC1000	pan-cancer	AAC	0.11	0.002
mRNA	CD151	GDSC1000	pan-cancer	AAC	0.13	0.002
mRNA	PLEKHJ1	GDSC1000	pan-cancer	AAC	-0.11	0.002
mRNA	PGBD5	GDSC1000	pan-cancer	AAC	-0.11	0.002
mRNA	INSL3	FIMM	pan-cancer	AAC	0.52	0.003

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