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Pazopanib

Pazopanib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Pazopanib
PharmacoGx	Pazopanib

External IDs

Database	Identifier
Smiles:	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Inchikey:	MQHIQUBXFFAOMK-UHFFFAOYSA-N
Pubchem:	11525740

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Pazopanib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CADPS2	GDSC1000	pan-cancer	AAC	-0.11	0.002
mRNA	MAP3K12	GDSC1000	pan-cancer	AAC	0.12	0.002
mRNA	GADD45G	GDSC1000	pan-cancer	AAC	-0.11	0.002
mRNA	ANPEP	GDSC1000	pan-cancer	AAC	0.11	0.002
mRNA	TRAF4	GDSC1000	pan-cancer	AAC	-0.11	0.002
mRNA	SUV39H2	FIMM	pan-cancer	AAC	0.56	0.002
mRNA	SPSB2	GDSC1000	pan-cancer	AAC	0.11	0.002
mRNA	RAB31	GDSC1000	pan-cancer	AAC	0.12	0.002
mRNA	TAP1	FIMM	pan-cancer	AAC	-0.51	0.002
mRNA	FRAS1	GDSC1000	pan-cancer	AAC	-0.11	0.002

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