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Pazopanib

Pazopanib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Pazopanib
PharmacoGx	Pazopanib

External IDs

Database	Identifier
Smiles:	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Inchikey:	MQHIQUBXFFAOMK-UHFFFAOYSA-N
Pubchem:	11525740

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Pazopanib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	NAP1L1	FIMM	pan-cancer	AAC	0.46	0.01
mRNA	COMT	GDSC1000	pan-cancer	AAC	0.085	0.01
mRNA	SIGLEC5	FIMM	pan-cancer	AAC	0.47	0.01
mRNA	TMEM74	GDSC1000	pan-cancer	AAC	-0.087	0.01
mRNA	TCIRG1	FIMM	pan-cancer	AAC	-0.49	0.01
mRNA	TMEM200B	GDSC1000	pan-cancer	AAC	0.087	0.01
mRNA	HRNR	GDSC1000	pan-cancer	AAC	0.081	0.01
mRNA	TMEM165	FIMM	pan-cancer	AAC	0.43	0.01
mRNA	E2F2	GDSC1000	pan-cancer	AAC	-0.097	0.01
mRNA	SMG5	GDSC1000	pan-cancer	AAC	-0.083	0.01

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