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Pazopanib

Pazopanib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Pazopanib
PharmacoGx	Pazopanib

External IDs

Database	Identifier
Smiles:	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Inchikey:	MQHIQUBXFFAOMK-UHFFFAOYSA-N
Pubchem:	11525740

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Pazopanib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RIC3	GDSC1000	pan-cancer	AAC	-0.087	0.01
mRNA	ZNF283	GDSC1000	pan-cancer	AAC	0.084	0.01
mRNA	POT1	GDSC1000	pan-cancer	AAC	-0.088	0.01
mRNA	PPM1B	GDSC1000	pan-cancer	AAC	-0.09	0.01
mRNA	PNN	GDSC1000	pan-cancer	AAC	-0.095	0.01
mRNA	ARHGAP22	GDSC1000	pan-cancer	AAC	0.088	0.01
mRNA	CCP110	GDSC1000	pan-cancer	AAC	-0.09	0.01
mRNA	NID1	GDSC1000	pan-cancer	AAC	0.093	0.01
mRNA	DCN	GDSC1000	pan-cancer	AAC	0.086	0.01
mRNA	GATA2	FIMM	pan-cancer	AAC	0.42	0.01

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