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Pazopanib

Pazopanib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Pazopanib
PharmacoGx	Pazopanib

External IDs

Database	Identifier
Smiles:	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Inchikey:	MQHIQUBXFFAOMK-UHFFFAOYSA-N
Pubchem:	11525740

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Pazopanib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	OTOR	GDSC1000	pan-cancer	AAC	0.11	0.0009
mRNA	VENTX	GDSC1000	pan-cancer	AAC	0.12	0.0009
mRNA	DCUN1D4	GDSC1000	pan-cancer	AAC	0.11	0.001
mRNA	DECR2	GDSC1000	pan-cancer	AAC	0.11	0.001
mRNA	ANKRD28	GDSC1000	pan-cancer	AAC	0.12	0.001
mRNA	ERCC2	GDSC1000	pan-cancer	AAC	0.11	0.001
mRNA	PDE6B	FIMM	pan-cancer	AAC	0.66	0.001
mRNA	MYOZ3	FIMM	pan-cancer	AAC	0.58	0.001
mRNA	LAMA2	GDSC1000	pan-cancer	AAC	0.11	0.001
mRNA	GBGT1	GDSC1000	pan-cancer	AAC	0.11	0.001

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