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Pazopanib

Pazopanib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Pazopanib
PharmacoGx	Pazopanib

External IDs

Database	Identifier
Smiles:	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Inchikey:	MQHIQUBXFFAOMK-UHFFFAOYSA-N
Pubchem:	11525740

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Pazopanib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MYOM2	GDSC1000	pan-cancer	AAC	-0.13	0.0004
mRNA	PRRX1	GDSC1000	pan-cancer	AAC	0.14	0.0004
mRNA	C1S	GDSC1000	pan-cancer	AAC	0.14	0.0004
mRNA	WWTR1	GDSC1000	pan-cancer	AAC	0.16	0.0004
mRNA	FKBP9	GDSC1000	pan-cancer	AAC	0.14	0.0004
mRNA	M1AP	GDSC1000	pan-cancer	AAC	0.12	0.0004
mRNA	ERMAP	GDSC1000	pan-cancer	AAC	0.12	0.0004
mRNA	PCSK2	GDSC1000	pan-cancer	AAC	-0.13	0.0004
mRNA	FGF10	GDSC1000	pan-cancer	AAC	0.18	0.0004
mRNA	NUP62CL	GDSC1000	pan-cancer	AAC	-0.14	0.0004

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