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Pazopanib

Pazopanib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Pazopanib
PharmacoGx	Pazopanib

External IDs

Database	Identifier
Smiles:	CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Inchikey:	MQHIQUBXFFAOMK-UHFFFAOYSA-N
Pubchem:	11525740

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Pazopanib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	HOOK1	GDSC1000	pan-cancer	AAC	-0.16	9e-05
mRNA	COL1A1	GDSC1000	pan-cancer	AAC	0.15	9e-05
mRNA	CUBN	GDSC1000	pan-cancer	AAC	0.14	9e-05
mRNA	STYX	GDSC1000	pan-cancer	AAC	0.13	0.0001
mRNA	ELAVL4	GDSC1000	pan-cancer	AAC	-0.17	0.0001
mRNA	OCIAD2	GDSC1000	pan-cancer	AAC	-0.15	0.0001
mRNA	TCF21	GDSC1000	pan-cancer	AAC	0.13	0.0001
mRNA	PRKG1	GDSC1000	pan-cancer	AAC	0.14	0.0001
mRNA	CXCL12	GDSC1000	pan-cancer	AAC	0.13	0.0001
mRNA	COL18A1	GDSC1000	pan-cancer	AAC	0.16	0.0001

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