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AUY922

AUY922

Synonyms

Sources	Names Used
GDSC1000	AUY922
PharmacoGx	AUY922

External IDs

Database	Identifier
Smiles:	CCNC(=O)C1=C(C(=C2C=C(C(=CC2=O)O)C(C)C)ON1)C3=CC=C(C=C3)CN4CCOCC4
Inchikey:	SWDZPNJZKUGIIH-QQTULTPQSA-N
Pubchem:	10096043

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AUY922

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	WDFY2	GDSC1000	pan-cancer	AAC	0.2	1e-08
mRNA	GPX8	GDSC1000	pan-cancer	AAC	0.21	2e-05
mRNA	LARP6	GDSC1000	pan-cancer	AAC	0.21	1e-05
mRNA	IGF2BP2	GDSC1000	pan-cancer	AAC	0.21	4e-07
mRNA	WWC2	GDSC1000	pan-cancer	AAC	0.21	7e-07
mRNA	TNFRSF12A	GDSC1000	pan-cancer	AAC	0.21	2e-05
mRNA	TNFRSF1A	GDSC1000	pan-cancer	AAC	0.21	2e-08
mRNA	PROSER2	GDSC1000	pan-cancer	AAC	0.21	5e-07
mRNA	TGM2	GDSC1000	pan-cancer	AAC	0.21	7e-08
mRNA	PPP1R18	GDSC1000	pan-cancer	AAC	0.21	1e-07

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