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AUY922

AUY922

Synonyms

Sources	Names Used
GDSC1000	AUY922
PharmacoGx	AUY922

External IDs

Database	Identifier
Smiles:	CCNC(=O)C1=C(C(=C2C=C(C(=CC2=O)O)C(C)C)ON1)C3=CC=C(C=C3)CN4CCOCC4
Inchikey:	SWDZPNJZKUGIIH-QQTULTPQSA-N
Pubchem:	10096043

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AUY922

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	NMI	GDSC1000	pan-cancer	AAC	0.19	9e-07
mRNA	NOB1	GDSC1000	pan-cancer	AAC	0.19	1e-07
mRNA	TPBG	GDSC1000	pan-cancer	AAC	0.19	1e-05
mRNA	ATF1	GDSC1000	pan-cancer	AAC	0.19	5e-08
mRNA	TOR4A	GDSC1000	pan-cancer	AAC	0.2	6e-07
mRNA	ZNF354B	GDSC1000	pan-cancer	AAC	0.2	5e-08
mRNA	RAC2	GDSC1000	pan-cancer	AAC	0.2	2e-05
mRNA	S100A16	GDSC1000	pan-cancer	AAC	0.2	2e-05
mRNA	RGS10	GDSC1000	pan-cancer	AAC	0.2	1e-08
mRNA	ELK3	GDSC1000	pan-cancer	AAC	0.2	3e-08

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