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AUY922

AUY922

Synonyms

Sources	Names Used
GDSC1000	AUY922
PharmacoGx	AUY922

External IDs

Database	Identifier
Smiles:	CCNC(=O)C1=C(C(=C2C=C(C(=CC2=O)O)C(C)C)ON1)C3=CC=C(C=C3)CN4CCOCC4
Inchikey:	SWDZPNJZKUGIIH-QQTULTPQSA-N
Pubchem:	10096043

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AUY922

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PSTK	GDSC1000	pan-cancer	AAC	0.098	0.006
mRNA	RNF19A	GDSC1000	pan-cancer	AAC	-0.096	0.006
mRNA	BBOX1	GDSC1000	pan-cancer	AAC	-0.097	0.006
mRNA	PCSK5	GDSC1000	pan-cancer	AAC	-0.1	0.006
mRNA	HERC5	GDSC1000	pan-cancer	AAC	0.095	0.006
mRNA	PRRX1	GDSC1000	pan-cancer	AAC	-0.11	0.006
mRNA	ZNF446	GDSC1000	pan-cancer	AAC	-0.094	0.006
mRNA	C15orf48	GDSC1000	pan-cancer	AAC	0.11	0.006
mRNA	SP100	GDSC1000	pan-cancer	AAC	0.11	0.006
mRNA	SMCO2	GDSC1000	pan-cancer	AAC	0.097	0.006

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