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AUY922

AUY922

Synonyms

Sources	Names Used
GDSC1000	AUY922
PharmacoGx	AUY922

External IDs

Database	Identifier
Smiles:	CCNC(=O)C1=C(C(=C2C=C(C(=CC2=O)O)C(C)C)ON1)C3=CC=C(C=C3)CN4CCOCC4
Inchikey:	SWDZPNJZKUGIIH-QQTULTPQSA-N
Pubchem:	10096043

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AUY922

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	DCX	GDSC1000	pan-cancer	AAC	-0.19	7e-07
mRNA	CADPS	GDSC1000	pan-cancer	AAC	-0.18	7e-07
mRNA	WWC2	GDSC1000	pan-cancer	AAC	0.21	7e-07
mRNA	SLC35F2	GDSC1000	pan-cancer	AAC	0.18	8e-07
mRNA	PIEZO1	GDSC1000	pan-cancer	AAC	0.18	9e-07
mRNA	NMI	GDSC1000	pan-cancer	AAC	0.19	9e-07
mRNA	SHFM1	GDSC1000	pan-cancer	AAC	-0.17	9e-07
mRNA	SEZ6	GDSC1000	pan-cancer	AAC	-0.18	9e-07
mRNA	IFITM3	GDSC1000	pan-cancer	AAC	0.22	1e-06
mRNA	NPM3	GDSC1000	pan-cancer	AAC	0.17	1e-06

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