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AP-24534

Synonyms

SourcesNames Used
GDSC1000AP-24534
FIMMPonatinib
PharmacoGx AP-24534

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5
Inchikey: PHXJVRSECIGDHY-UHFFFAOYSA-N
Pubchem: 24826799

FDA Approval Status

Approved
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Top molecular features associated with response to AP-24534


Feature TypeStandardized
Nominal ANOVA
mRNA ITGAL GDSC1000 pan-cancer AAC 0.23 2e-07
mRNA KLF1 GDSC1000 pan-cancer AAC 0.17 2e-07
mRNA TMC8 GDSC1000 pan-cancer AAC 0.24 2e-07
mRNA NIPSNAP3B GDSC1000 pan-cancer AAC 0.18 3e-07
mRNA ATF7IP2 GDSC1000 pan-cancer AAC 0.18 3e-07
mRNA C1orf228 GDSC1000 pan-cancer AAC 0.19 4e-07
mRNA TNFRSF8 GDSC1000 pan-cancer AAC -0.18 4e-07
mRNA DPEP2 GDSC1000 pan-cancer AAC 0.18 4e-07
mRNA NLRC3 GDSC1000 pan-cancer AAC 0.25 4e-07
mRNA WT1 GDSC1000 pan-cancer AAC 0.17 5e-07
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