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AP-24534

Synonyms

SourcesNames Used
GDSC1000AP-24534
FIMMPonatinib
PharmacoGx AP-24534

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5
Inchikey: PHXJVRSECIGDHY-UHFFFAOYSA-N
Pubchem: 24826799

FDA Approval Status

Approved
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Top molecular features associated with response to AP-24534


Feature TypeStandardized
Nominal ANOVA
mRNA RBM11 GDSC1000 pan-cancer AAC -0.091 0.02
mRNA C19orf18 GDSC1000 pan-cancer AAC 0.077 0.02
mRNA CHST3 GDSC1000 pan-cancer AAC 0.084 0.02
mRNA FAM71E2 GDSC1000 pan-cancer AAC 0.075 0.02
mRNA NDUFA2 GDSC1000 pan-cancer AAC -0.078 0.02
mRNA FRMD4B GDSC1000 pan-cancer AAC -0.079 0.02
mRNA TET3 GDSC1000 pan-cancer AAC 0.085 0.02
mRNA DNAH7 GDSC1000 pan-cancer AAC -0.074 0.02
mRNA NAA40 GDSC1000 pan-cancer AAC 0.079 0.02
mRNA NTMT1 GDSC1000 pan-cancer AAC -0.076 0.02
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