1. Home/
  2. Compounds/
  3. AP-24534

AP-24534

Synonyms

SourcesNames Used
GDSC1000AP-24534
FIMMPonatinib
PharmacoGx AP-24534

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5
Inchikey: PHXJVRSECIGDHY-UHFFFAOYSA-N
Pubchem: 24826799

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to AP-24534


Feature TypeStandardized
Nominal ANOVA
mRNA PHC2 GDSC1000 pan-cancer AAC 0.086 0.02
mRNA TGFB1 FIMM pan-cancer AAC 0.51 0.02
mRNA MIS18BP1 GDSC1000 pan-cancer AAC 0.089 0.02
mRNA TET2 GDSC1000 pan-cancer AAC 0.081 0.02
mRNA CDC14A FIMM pan-cancer AAC 0.55 0.02
mRNA SNAPC5 GDSC1000 pan-cancer AAC -0.079 0.02
mRNA ZBTB45 GDSC1000 pan-cancer AAC 0.078 0.02
mRNA CD36 GDSC1000 pan-cancer AAC 0.076 0.02
mRNA DOCK5 GDSC1000 pan-cancer AAC 0.083 0.02
mRNA C4orf3 GDSC1000 pan-cancer AAC 0.079 0.02
Download CSV