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AP-24534

Synonyms

SourcesNames Used
GDSC1000AP-24534
FIMMPonatinib
PharmacoGx AP-24534

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5
Inchikey: PHXJVRSECIGDHY-UHFFFAOYSA-N
Pubchem: 24826799

FDA Approval Status

Approved
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Top molecular features associated with response to AP-24534


Feature TypeStandardized
Nominal ANOVA
mRNA KDELC2 GDSC1000 pan-cancer AAC 0.087 0.02
mRNA GALNT7 FIMM pan-cancer AAC 0.38 0.02
mRNA FASTK GDSC1000 pan-cancer AAC -0.083 0.02
mRNA TTLL10 GDSC1000 pan-cancer AAC 0.08 0.02
mRNA RPL22 FIMM pan-cancer AAC 0.41 0.02
mRNA NCKAP5L GDSC1000 pan-cancer AAC 0.081 0.02
mRNA ZNF416 GDSC1000 pan-cancer AAC 0.077 0.02
mRNA CNTN6 FIMM pan-cancer AAC 0.43 0.02
mRNA STYXL1 FIMM pan-cancer AAC -0.4 0.02
mRNA KRTAP26-1 GDSC1000 pan-cancer AAC 0.077 0.02
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