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AP-24534

Synonyms

SourcesNames Used
GDSC1000AP-24534
FIMMPonatinib
PharmacoGx AP-24534

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5
Inchikey: PHXJVRSECIGDHY-UHFFFAOYSA-N
Pubchem: 24826799

FDA Approval Status

Approved
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Top molecular features associated with response to AP-24534


Feature TypeStandardized
Nominal ANOVA
mRNA TMEM161B GDSC1000 pan-cancer AAC -0.12 0.0009
mRNA ASAP2 GDSC1000 pan-cancer AAC -0.16 0.0009
mRNA TMEM217 GDSC1000 pan-cancer AAC 0.11 0.0009
mRNA EFNA5 GDSC1000 pan-cancer AAC -0.13 0.0009
mRNA ALG14 GDSC1000 pan-cancer AAC -0.11 0.0009
mRNA CNTRL GDSC1000 pan-cancer AAC 0.14 0.0009
mRNA MMRN1 FIMM pan-cancer AAC 0.56 0.0009
mRNA MBD2 GDSC1000 pan-cancer AAC -0.12 0.0009
mRNA STK38 GDSC1000 pan-cancer AAC 0.11 0.0009
mRNA RRNAD1 GDSC1000 pan-cancer AAC -0.11 0.0009
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