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AP-24534

Synonyms

SourcesNames Used
GDSC1000AP-24534
FIMMPonatinib
PharmacoGx AP-24534

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5
Inchikey: PHXJVRSECIGDHY-UHFFFAOYSA-N
Pubchem: 24826799

FDA Approval Status

Approved
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Top molecular features associated with response to AP-24534


Feature TypeStandardized
Nominal ANOVA
mRNA TBC1D1 GDSC1000 pan-cancer AAC 0.12 0.0008
mRNA GNPDA1 GDSC1000 pan-cancer AAC -0.13 0.0009
mRNA SPATS2 GDSC1000 pan-cancer AAC -0.11 0.0009
mRNA RNF24 GDSC1000 pan-cancer AAC 0.11 0.0009
mRNA NFATC3 GDSC1000 pan-cancer AAC 0.14 0.0009
mRNA LTB4R2 GDSC1000 pan-cancer AAC 0.11 0.0009
mRNA PPM1H GDSC1000 pan-cancer AAC -0.12 0.0009
mRNA CFAP57 GDSC1000 pan-cancer AAC -0.11 0.0009
mRNA ZNF235 GDSC1000 pan-cancer AAC 0.11 0.0009
mRNA KIAA0922 GDSC1000 pan-cancer AAC 0.14 0.0009
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