Home/
Compounds/
AP-24534

AP-24534

Synonyms

Sources	Names Used
GDSC1000	AP-24534
FIMM	Ponatinib
PharmacoGx	AP-24534

External IDs

Database	Identifier
Smiles:	CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5
Inchikey:	PHXJVRSECIGDHY-UHFFFAOYSA-N
Pubchem:	24826799

FDA Approval Status

Approved

Dataset Select

Download Data as CSV

Top molecular features associated with response to AP-24534

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MRPL24	GDSC1000	pan-cancer	AAC	-0.08	0.02
mRNA	IL17F	GDSC1000	pan-cancer	AAC	-0.075	0.02
mRNA	RAB36	GDSC1000	pan-cancer	AAC	-0.076	0.02
mRNA	MIER1	GDSC1000	pan-cancer	AAC	0.079	0.02
mRNA	ST3GAL3	GDSC1000	pan-cancer	AAC	0.079	0.02
mRNA	PDIA6	GDSC1000	pan-cancer	AAC	-0.077	0.02
mRNA	COPB2	GDSC1000	pan-cancer	AAC	-0.079	0.02
mRNA	ADAM32	GDSC1000	pan-cancer	AAC	0.077	0.02
mRNA	C10orf76	GDSC1000	pan-cancer	AAC	0.077	0.02
mRNA	TREX1	GDSC1000	pan-cancer	AAC	-0.086	0.02

← Previous 1 2…187188189…199 200 Next →