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Midostaurin

Synonyms

SourcesNames Used
GDSC1000Midostaurin
PharmacoGx Midostaurin

External IDs

DatabaseIdentifier
Smiles: CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
Inchikey: BMGQWWVMWDBQGC-PZFYLCKJSA-N
Pubchem: 24202429

Annotated Targets

KIT, FLT3, PRKCG

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Midostaurin


Feature TypeStandardized
Nominal ANOVA
mRNA SOCS5 GDSC1000 pan-cancer AAC 0.22 6e-09
mRNA LOXL2 GDSC1000 pan-cancer AAC 0.24 7e-09
mRNA ITGB1 GDSC1000 pan-cancer AAC 0.25 7e-09
mRNA PROSER1 GDSC1000 pan-cancer AAC -0.23 8e-09
mRNA NEXN GDSC1000 pan-cancer AAC 0.22 8e-09
mRNA ACTN1 GDSC1000 pan-cancer AAC 0.25 9e-09
mRNA GBE1 GDSC1000 pan-cancer AAC 0.22 9e-09
mRNA MMP14 GDSC1000 pan-cancer AAC 0.25 1e-08
mRNA IGFBP7 GDSC1000 pan-cancer AAC 0.22 1e-08
mRNA MXRA8 GDSC1000 pan-cancer AAC 0.2 1e-08
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