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Midostaurin

Synonyms

SourcesNames Used
GDSC1000Midostaurin
PharmacoGx Midostaurin

External IDs

DatabaseIdentifier
Smiles: CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
Inchikey: BMGQWWVMWDBQGC-PZFYLCKJSA-N
Pubchem: 24202429

Annotated Targets

KIT, FLT3, PRKCG

FDA Approval Status

Approved
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Top molecular features associated with response to Midostaurin


Feature TypeStandardized
Nominal ANOVA
mRNA LPAR4 GDSC1000 pan-cancer AAC 0.097 0.006
mRNA CTSL GDSC1000 pan-cancer AAC 0.12 0.006
mRNA MAP7 GDSC1000 pan-cancer AAC -0.12 0.006
mRNA GGT5 GDSC1000 pan-cancer AAC 0.091 0.006
mRNA DACH1 GDSC1000 pan-cancer AAC -0.098 0.006
mRNA WISP2 GDSC1000 pan-cancer AAC 0.096 0.006
mRNA CEP131 GDSC1000 pan-cancer AAC -0.098 0.006
mRNA RNF181 GDSC1000 pan-cancer AAC 0.095 0.006
mRNA ZNF589 GDSC1000 pan-cancer AAC -0.11 0.006
mRNA UQCR10 GDSC1000 pan-cancer AAC -0.093 0.006
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