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Midostaurin

Synonyms

SourcesNames Used
GDSC1000Midostaurin
PharmacoGx Midostaurin

External IDs

DatabaseIdentifier
Smiles: CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
Inchikey: BMGQWWVMWDBQGC-PZFYLCKJSA-N
Pubchem: 24202429

Annotated Targets

KIT, FLT3, PRKCG

FDA Approval Status

Approved
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Top molecular features associated with response to Midostaurin


Feature TypeStandardized
Nominal ANOVA
mRNA WDR1 GDSC1000 pan-cancer AAC 0.19 4e-07
mRNA RRAS GDSC1000 pan-cancer AAC 0.22 4e-07
mRNA ERCC2 GDSC1000 pan-cancer AAC 0.17 4e-07
mRNA AZU1 GDSC1000 pan-cancer AAC 0.18 4e-07
mRNA RNASE3 GDSC1000 pan-cancer AAC 0.18 4e-07
mRNA QSOX1 GDSC1000 pan-cancer AAC 0.19 4e-07
mRNA AC013461.1 GDSC1000 pan-cancer AAC 0.18 4e-07
mRNA CYBRD1 GDSC1000 pan-cancer AAC 0.18 5e-07
mRNA ERRFI1 GDSC1000 pan-cancer AAC 0.26 5e-07
mRNA SFXN3 GDSC1000 pan-cancer AAC 0.19 5e-07
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