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Midostaurin

Synonyms

SourcesNames Used
GDSC1000Midostaurin
PharmacoGx Midostaurin

External IDs

DatabaseIdentifier
Smiles: CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
Inchikey: BMGQWWVMWDBQGC-PZFYLCKJSA-N
Pubchem: 24202429

Annotated Targets

KIT, FLT3, PRKCG

FDA Approval Status

Approved
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Top molecular features associated with response to Midostaurin


Feature TypeStandardized
Nominal ANOVA
mRNA CXXC5 GDSC1000 pan-cancer AAC 0.098 0.005
mRNA GTPBP1 GDSC1000 pan-cancer AAC -0.1 0.005
mRNA TFPI GDSC1000 pan-cancer AAC 0.11 0.005
mRNA RAPGEF5 GDSC1000 pan-cancer AAC -0.1 0.005
mRNA FNBP1L GDSC1000 pan-cancer AAC -0.12 0.005
mRNA TPBG GDSC1000 pan-cancer AAC 0.12 0.005
mRNA GLOD4 GDSC1000 pan-cancer AAC -0.097 0.005
mRNA RGS1 GDSC1000 pan-cancer AAC -0.1 0.005
mRNA HIST1H1E GDSC1000 pan-cancer AAC -0.099 0.005
mRNA RANBP10 GDSC1000 pan-cancer AAC -0.1 0.005
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