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Midostaurin

Synonyms

SourcesNames Used
GDSC1000Midostaurin
PharmacoGx Midostaurin

External IDs

DatabaseIdentifier
Smiles: CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
Inchikey: BMGQWWVMWDBQGC-PZFYLCKJSA-N
Pubchem: 24202429

Annotated Targets

KIT, FLT3, PRKCG

FDA Approval Status

Approved
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Top molecular features associated with response to Midostaurin


Feature TypeStandardized
Nominal ANOVA
mRNA HERC4 GDSC1000 pan-cancer AAC 0.17 9e-07
mRNA EMP3 GDSC1000 pan-cancer AAC 0.2 9e-07
mRNA TAGLN3 GDSC1000 pan-cancer AAC -0.19 9e-07
mRNA KLHL23 GDSC1000 pan-cancer AAC -0.19 1e-06
mRNA CHN2 GDSC1000 pan-cancer AAC -0.17 1e-06
mRNA HSPG2 GDSC1000 pan-cancer AAC 0.19 1e-06
mRNA THBS2 GDSC1000 pan-cancer AAC 0.19 1e-06
mRNA SERPINH1 GDSC1000 pan-cancer AAC 0.21 1e-06
mRNA TOX3 GDSC1000 pan-cancer AAC -0.18 1e-06
mRNA ITGA3 GDSC1000 pan-cancer AAC 0.2 1e-06
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