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Midostaurin

Synonyms

SourcesNames Used
GDSC1000Midostaurin
PharmacoGx Midostaurin

External IDs

DatabaseIdentifier
Smiles: CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
Inchikey: BMGQWWVMWDBQGC-PZFYLCKJSA-N
Pubchem: 24202429

Annotated Targets

KIT, FLT3, PRKCG

FDA Approval Status

Approved
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Top molecular features associated with response to Midostaurin


Feature TypeStandardized
Nominal ANOVA
mRNA RHOH GDSC1000 pan-cancer AAC -0.27 6e-07
mRNA GADD45G GDSC1000 pan-cancer AAC -0.18 6e-07
mRNA ANKRD28 GDSC1000 pan-cancer AAC 0.18 6e-07
mRNA PRSS57 GDSC1000 pan-cancer AAC 0.18 6e-07
mRNA CCR2 GDSC1000 pan-cancer AAC 0.17 6e-07
mRNA CHD7 GDSC1000 pan-cancer AAC -0.19 7e-07
mRNA LPAR1 GDSC1000 pan-cancer AAC 0.19 7e-07
mRNA BDNF GDSC1000 pan-cancer AAC 0.19 7e-07
mRNA FLII GDSC1000 pan-cancer AAC 0.19 7e-07
mRNA CHGA GDSC1000 pan-cancer AAC -0.21 7e-07
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